2009 Feb 27- ☣️ 'Nanoparticles for nasal vaccination- 😷
Abstract: "The great interest in mucosal vaccine delivery arises from the fact that mucosal surfaces represent the major site of entry for many pathogens. Among other mucosal sites, nasal delivery is especially attractive for immunization, as the nasal epithelium is characterized by relatively high permeability, low enzymatic activity and by the presence of an important number of immunocompetent cells.
In addition to these advantageous characteristics, the nasal route could offer simplified and more cost-effective protocols for vaccination with improved patient compliance. The use of nanocarriers provides a suitable way for the nasal delivery of antigenic molecules. Besides improved protection and facilitated transport of the antigen, nanoparticulate delivery systems could also provide more effective antigen recognition by immune cells.
These represent key factors in the optimal processing and presentation of the antigen, and therefore in the subsequent development of a suitable immune response. In this sense, the design of optimized vaccine nanocarriers offers a promising way for nasal mucosal vaccination...." - https://pubmed.ncbi.nlm.nih.gov/19121350/
🤠iffin you gonna move down or remain in Ecuador on into 2025, get prepared for whats a coming down the pike🥷🏼its not and has not been just a Coastal & #GYE thang, its also a Sierra & Metro #Quito Thanggy as well👮🏻♂️💰
My 2025 NewYears Resolution is more time out on the La G range, zz style, 🎸🥁🎸 cuzz (imho) we gonna dang sure be a needin it🥷🏼if anybody wants to no longer be an outlaw? Call me to join our Qtowne Quito gun club and get legal to tote with a 55hr CCW Course,
now a days The CCW is pretty much streamlined down to this:
plan on about $300 for to join the gun club,about $200 or up to $300 for the CCW course,about $300 for psyche, psycho and toxico exams,
a 9mm Taurus for say $1200.
a 9mm CZ for say $1500.
aprox $80 to $100 for a box of 50rds 9mm FMJ
i see peeps now a days getting legally armed in about a 3-4 months time frame, kinda like a tuff assed visa process!
'Always be prepared' - BSA & SA,
"When guns are outlawed, only outlaws will have guns" - Louis L'Amour (1908-1988) Western novelist of ...
20AUG25 'The 10 most affordable states for retirees in 2025- "Here are the most affordable states, according to Bankrate’s analysis:
West Virginia
Pennsylvania
Delaware
Wyoming
Ohio
Wisconsin
Nevada
Indiana
Idaho
Georgia,
West Virginia
powered to the top with strong performances in both key sub-categories. The state had the lowest cost of living, as well as the fourth-lowest cost of homeowner’s insurance, at $1,009 annually.
“West Virginia has been an attractive location for retirees for the last few years and has seen multiple years of positive net migration — people moving in — despite the fact that the overall state population is shrinking,” says Kates...." -
Premeirs🎥SUN 10AUG25 (9pmET) #CNN "Senior National Correspondent David Culver and team report on the exploding violence in Ecuador, 🇪🇨
Where citizens are regularly pressured to hand over money to gangs involved in the country’s drug trade.
Watch ‘Ecuador: The Narco Superhighway’ on ‘The Whole Story with Anderson Cooper’ Sunday August 10 at 9pm ET on CNN." #CNN #News -
